Wednesday, May 6, 2020

Review of Research Paper on Parkinsons Disease Treatment

Abstract Attempts to cure or slow down the progression of Parkinson’s disease have largely failed; researchers in this paper maintain this is obviously a direct result of the lack of insight into the pathogenesis of the disease. Parkinson’s disease is the product of the deaths of a number of dopaminergic (dopamine-secreting) neurons in the substantia nigra pars compacta region (SNc) of the brain. But what causes these deaths? In the paper â€Å"‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease,† Chen and researchers find that older neurons in the SNc are unusually reliant on calcium channels and that after blocking these channels, the cells are â€Å"rejuvenated† and begin acting like their juvenile counterparts; as a†¦show more content†¦Ã¢â‚¬ ¢ Age This is due to the fact that they are in the environment longer and their genes are having more time to mutate from sun exposure, unhealthy living styles, and free radicals. †¢ Sex Men are at a higher risk than women †¢ Diet 1. Should be high in green leafy vegetables 2. Eat a balance of other vegetables and fruits 3. Avoid caffeine, tobacco, and sugar †¢ Yoga 1. Motor skills †¢ Acupuncture 1. Established correct balance of yin and yang 2. Brings harmony back to the body †¢ Antioxidants Used to reduce the negative effects that the environment has on the body What is Parkinsons? 1. A disease of the brain caused by a lack of the chemical dopamine 2. Dopamine allows the muscles of the body to function properly (i.e. smoothly) 3. The lack of this chemical is caused by the death of the nerve cells that produce dopamine (substantia nigra) o When dopamine producing cells are reduced by 80%, the physical symptoms of Parkinson’s present themselves Diagnosis, Symptoms, and Treatment Diagnosis There is no definitive test that can diagnose Parkinson’s disease (PD). Diagnoses by physicians are usually made by looking at a patient’s medical history, observing for particular signs, and performing a comprehensive neurological exam. It can be difficult, however, as the principal symptoms of PD can be similar to those caused by certain medications or other degenerative brainShow MoreRelatedA Red Shifted Variant Of Channelrhodopsin Allows Deep Transcranial Optogenetic Excitation770 Words   |  4 PagesLin, J.Y., Magne Knutsen, P., Muller, A., Kleinfeld, D., Tsien, R.Y. 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